Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction
Rev. Soc. Bras. Med. Trop
; 47(4): 533-536, Jul-Aug/2014. graf
Article
in English
| LILACS
| ID: lil-722298
Responsible library:
BR1.1
ABSTRACT
Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.5: Prevention and treatment of consumption of psychoactive substances
Database:
LILACS
Main subject:
Aspergillosis
/
Sinusitis
/
Rhinitis
/
Nose Deformities, Acquired
/
Cocaine-Related Disorders
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2014
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Santa Casa de Misericórdia do Rio de Janeiro/BR