Actividad Antibacteriana in vitro de extractos y fracciones de Physalis peruviana L. y Caesalpinia pulcherrima (L.) Swartz / In vitro antibacterial activity of extracts and fractions of Physalis peruviana L. and Caesalpinia pulcherrima (L.) Swartz
Bol. latinoam. Caribe plantas med. aromát
; 12(3): 230-237, mayo 2013. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-723569
Responsible library:
CL1.1
ABSTRACT
We evaluated the in vitro antibacterial activity of extracts and fractions of Physalis peruviana L. calyces and flowers and leaves of Caesalpinia pulcherrima (L.) Swartz against ATCC strains Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa, determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). We find potent activity with MIC < 0,256 mg/mL for the chloroform fraction of P. peruviana calyces, the ethanol fraction of flowers of C. pulcherrima and ethanol and ether fractions of leaves of C. pulcherrima. Based on these results, we conclude that both species are promising and it is recommended to continue exploring them in order to isolate, purify and to elucidate the chemical structure from those compounds responsible for the biological activity of each active fraction.
RESUMEN
Se evaluó la actividad antibacteriana in vitro de extractos y fracciones de los cálices de Physalis peruviana L. y flores y hojas de Caesalpinia pulcherrima (L.) Swartz frente a cepas ATCC de Staphylococcus aureus, Klebsiella pneumoniae y Pseudomonas aeruginosa, determinando la concentración mínima inhibitoria (CMI) y la concentración mínima bactericida (CMB). Encontramos potente actividad, con valores de CMI < 0,256 mg/mL para la fracción en cloroformo de los cálices de P. peruviana, la fracción en etanol de las flores de C. pulcherrima y las fracciones en etanol y éter de las hojas de C. pulcherrima. En función de los resultados obtenidos, concluimos que ambas especies son promisorias y se recomienda continuar su estudio intentando aislar, purificar y dilucidar la estructura química de los compuestos responsables de la actividad biológica en cada fracción activa.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
LILACS
Main subject:
Plant Extracts
/
Caesalpinia
/
Physalis
/
Anti-Bacterial Agents
Language:
Spanish
Journal:
Bol. latinoam. Caribe plantas med. aromát
Journal subject:
Botany
/
Medicine
/
Plantas Medicinais
/
Terapias Complementares
Year:
2013
Document type:
Article
Affiliation country:
Colombia
Institution/Affiliation country:
Universidad de Cartagena/CO