Antibacterial activity of flavonoid 5.7.4-trimethoxyflavone isolated from Praxelis clematides R.M. King & Robinson / Actividad antibacterial del flavonoide 5.7.4-trimetoxiflavona aislada dePrexelis clematides R.M. King & Robinson
Bol. latinoam. Caribe plantas med. aromát
; 12(4): 400-404, jul. 2013. tab
Article
in English
| LILACS
| ID: lil-724333
Responsible library:
CL1.1
ABSTRACT
The flavonoids are a large class of polyphenolic compounds found in plants that are known to exhibit biological effects. In the study, the flavonoid 5.7.4-trimethoxyflavone (TMF) extracted from Praxelis clematidea was evaluated for its antibacterial activity. Microdilution method was used for antibacterial assay of the flavonoid and eleven bacteria strains were used in the study for activities. The results were also compared with the standard drug, Chloramphenicol (100 ug/mL). The results obtained showed activity of the flavonoid against Gram positive and Gram negative bacteria.
RESUMEN
Los flavonoides son una clase importante de compuestos polifenólicos encontrados en las plantas que se sabe que presentan efectos biológicos. En el estudio, el flavonoide 5.7.4 '-trimethoxyflavone (TMF) extraído de Praxelis clematidea fue evaluado por su actividad antibacteriana. Se utilizó el método de microdilución para el ensayo antibacteriano del flavonoide y once cepas de bacterias se usaron en el estudio de las actividades. Los resultados se compararon también con el fármaco estándar, Cloranfenicol (100 ug/mL). Los resultados obtenidos mostraron actividad del flavonoide contra bacterias Gram positivas y Gram negativas.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Plants, Medicinal
/
Flavonoids
/
Asteraceae
/
Anti-Bacterial Agents
Language:
English
Journal:
Bol. latinoam. Caribe plantas med. aromát
Journal subject:
Botany
/
Medicine
/
Plantas Medicinais
/
Terapias Complementares
Year:
2013
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Paraiba/BR
/
Federal University of São Francisco Valley/BR