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Relación entre la edad materna avanzada y la morbilidad neonatal en el Hospital Nacional Arzobispo Loayza. Enero-Octubre del 2012 / Relationship between advanced maternal age and neonatal morbidity in the Hospital Nacional Arzobispo Loayza between January and October 2012
Lemor, Alejandro.
Affiliation
  • Lemor, Alejandro; Harvard Medical School. US
Horiz. méd. (Impresa) ; 14(2): 22-26, jul. 2014. tab
Article in Spanish | LILACS, LIPECS | ID: lil-728037
Responsible library: PE1.1
RESUMEN

Objetivo:

Determinar si existe relación entre la edad materna avanzada y la morbilidad neonatal en el Hospital Nacional Arzobispo Loayza. Material y

Métodos:

Estudio tipo cohorte, comparativo, analítico, retrospectivo. Se utilizó una muestra de 2771 recién nacidos entre Enero y Octubre del 2012, de los cuales fueron 460 de madres mayores de 35 años y 2311 de madres entre 20 y 34 años. El análisis estadístico utilizó SPSS 21.0 y se incluyó la prueba de chi cuadrado, siendo un valor de p < 0.05 considerado para la significancia estadística.

Resultados:

El 1.3% de los recién nacidos de madres añosas presentaron trisomía 21, en comparación con un 0.13% en las madres de 20 a 34 años (p < 0.001; RR 10.16 IC 95% 2.5 - 40.8). El parto por cesárea representó el 51.52% en el grupo de mayores de 35 y 37.78% en el grupo control (p< 0.001; RR 1.75 , IC 95% 1.43 - 2.14). No se halló diferencia significativa al comparar el resto de morbilidades en ambos grupos, siendo estas la Enfermedad de Membrana Hialina (p=0.824),Síndrome de Distrés Respiratorio (p=0.448), Sepsis Neonatal (p=0.309).

Conclusiones:

La edad materna avanzada se asoció con una mayor tasa de cesáreas y más riesgo de tener un hijo con síndrome de Down. No se evidenció que la edad materna avanzada se asocie al aumento de la morbimortalidad neonatal.
ABSTRACT

Objective:

Determine the relationship between advanced maternal age and neonatal morbidity in the Hospital Nacional Arzobispo Loayza. Material and

Methods:

Cohort study, comparative, analytical, retrospective. A total of 2771 infants between January and October 2012 were included in the study; of which 460 were born of mothers aged over 35 and 2311 of mothers between 20 and 34 years. Statistical analysis used SPSS 21.0 and included the chi-square test, considering a p value of <0.05 for statistical significance.

Results:

1.3% of newborns of older mothers had trisomy 21, compared with 0.13% in mothers aged 20 to 34 years (p <0.001, RR 10.16, 95% CI 2.5 - 40.8). The cesarean delivery accounted for 51.52% in the group of aged over 35 and 37.78% in the control group (p <0.001, RR 1.75, 95% CI 1.43 - 2.14). There was no significant difference for other morbidities in both groups; hyaline membrane disease (p = 0.824), respiratory distress syndrome (p = 0.448) and neonatal sepsis (p = 0.309).

Conclusions:

Advanced maternal age was associated with a higher rate of C-sections and a higher risk of having a child with Down syndrome. There was no evidence that advanced maternal age is associated with increased neonatal morbidity.
Subject(s)

Full text: Available Collection: National databases / Peru Health context: SDG3 - Health and Well-Being / SDG3 - Target 3.1 Reduce Maternal Mortality / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Target 3.2: Reduce avoidable death in newborns and children under 5 / Obstetric Labor Complications / Congenital and Chromosomal Anomalies / Neonatal Healthcare Database: LILACS / LIPECS Main subject: Infant Mortality / Maternal Age / Down Syndrome / Pregnancy, High-Risk Type of study: Etiology study / Incidence study / Observational study / Risk factors Language: Spanish Journal: Horiz. méd. (Impresa) Year: 2014 Document type: Article Institution/Affiliation country: Harvard Medical School/US
Full text: Available Collection: National databases / Peru Health context: SDG3 - Health and Well-Being / SDG3 - Target 3.1 Reduce Maternal Mortality / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Target 3.2: Reduce avoidable death in newborns and children under 5 / Obstetric Labor Complications / Congenital and Chromosomal Anomalies / Neonatal Healthcare Database: LILACS / LIPECS Main subject: Infant Mortality / Maternal Age / Down Syndrome / Pregnancy, High-Risk Type of study: Etiology study / Incidence study / Observational study / Risk factors Language: Spanish Journal: Horiz. méd. (Impresa) Year: 2014 Document type: Article Institution/Affiliation country: Harvard Medical School/US
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