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Intrauterine growth restriction in monochorionic-diamniotic twins / Restrição de crescimento intrauterino em gêmeos monocoriônicos diamnióticos.
Machado, Rita de Cássia Alam; Brizot, Maria de Lourdes; Miyadahira, Seizo; Francisco, Rossana Pulcineli Vieira; Krebs, Vera Lúcia Jornada; Zugaib, Marcelo.
Affiliation
  • Machado, Rita de Cássia Alam; University of São Paulo’s Medical School. Hospital das Clínicas. Department of Obstetric. São Paulo. BR
  • Brizot, Maria de Lourdes; University of São Paulo’s Medical School. Hospital das Clínicas. Department of Obstetric. São Paulo. BR
  • Miyadahira, Seizo; University of São Paulo’s Medical School. Hospital das Clínicas. Department of Obstetric. São Paulo. BR
  • Francisco, Rossana Pulcineli Vieira; University of São Paulo’s Medical School. Hospital das Clínicas. Department of Obstetric. São Paulo. BR
  • Krebs, Vera Lúcia Jornada; University of São Paulo’s Medical School. Hospital das Clínicas. Department of Obstetric. São Paulo. BR
  • Zugaib, Marcelo; University of São Paulo’s Medical School. Hospital das Clínicas. Department of Obstetric. São Paulo. BR
Rev. Assoc. Med. Bras. (1992, Impr.) ; 60(6): 585-590, Nov-Dec/2014. tab
Article in English | LILACS | ID: lil-736320
Responsible library: BR1.1
ABSTRACT

Objective:

to evaluate neonatal morbidity and mortality in monochorionic- -diamniotic (MCDA) twin pregnancies complicated by selective intrauterine growth restriction (sIUGR) and non-selective intrauterine growth resctriction (nsIUGR).

Methods:

neonatal morbidity parameters and mortality were analyzed in 34 twins with IUGR (< 10th percentile on twinsgrowth charts) 18 with sIUGR and 16 with nsIUGR. The sIUGR group was made up of 18 pregnancies in which growth was restricted in only one fetus (n = 18). The nsIUGR group was composed of 8 pregnancies in which both fetuses presented restricted growth (n = 16). Cases of twin-to-twin transfusion syndrome and fetal malformation were not included in the study.

Results:

the MCDA twin pregnancies with sIUGR had a higher rate of orotracheal intubation (p = 0.001) and mechanical ventilation (p = 0.0006), as well as longer than average fasting time (p = 0.014) compared to those in which the fetuses had nsIUGR. A higher incidence was also observed of types II and III umbilical artery Doppler velocimetry patterns in the sIUGR cases (p = 0.002). There was no significant difference between the two groups as to mortality during pregnancy and the neonatal period (p = 0.09).

Conclusion:

in MCDA twin pregnancies, sIUGR presents more severe umbilical artery Doppler velocimetry abnormalities and worse morbidity than nsIUGR. .
RESUMO

Objetivo:

avaliar a morbidade e mortalidade neonatal em gestações monocoriônicas e diamnióticas (MCDA) acometidas pela restrição de crescimento fetal seletiva (RCFS) e não seletiva (RCFNS).

Métodos:

os parâmetros de morbidade e mortalidade neonatais foram avaliados em 34 gêmeos com RCF (abaixo do percentil 10 de uma curva de crescimento para gêgêmeos) 18 com RCFS e 16 com RCFNS. O grupo com RCFS teve origem em 18 gestações, em que somente um feto apresentava RCF. O grupo com RCFNS teve origem em 8 gestações em que ambos os fetos apresentavam RCF. Foram excluídos deste estudo casos da síndrome da transfusão feto-fetal e malformações fetais.

Resultados:

os gêmeos de gestações MCDA com RCFS apresentaram maior frequência de entubação orotraqueal (p=0,001), ventilação mecânica (p=0,0006) e maior tempo em jejum durante internação (p=0,014), quando comparados aos gêmeos de gestações MCDA com RCFNS. No grupo com RCFS, também foram observados maior frequência de tipos II e III de dopplervelocimetria de artéria umbilical (p=0,002). Não houve diferença significativa entre os grupos quanto à mortalidade neonatal (p=0,09).

Conclusão:

em gestações gemelares MCDA, a RCFS representa maior frequência de alterações severas na velocimetria Doppler da artéria umbilical e piores resultados na morbidade neonatal. .
Subject(s)


Full text: Available Collection: International databases Database: LILACS Main subject: Twins, Monozygotic / Umbilical Arteries / Perinatal Mortality / Fetal Growth Retardation Type of study: Etiology study / Incidence study / Observational study / Prognostic study / Risk factors Limits: Female / Humans / Male / Infant, Newborn / Pregnancy Country/Region as subject: South America / Brazil Language: English Journal: Rev. Assoc. Med. Bras. (1992, Impr.) Journal subject: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / Medicine Year: 2014 Document type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo&#8217;s Medical School/BR

Full text: Available Collection: International databases Database: LILACS Main subject: Twins, Monozygotic / Umbilical Arteries / Perinatal Mortality / Fetal Growth Retardation Type of study: Etiology study / Incidence study / Observational study / Prognostic study / Risk factors Limits: Female / Humans / Male / Infant, Newborn / Pregnancy Country/Region as subject: South America / Brazil Language: English Journal: Rev. Assoc. Med. Bras. (1992, Impr.) Journal subject: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / Medicine Year: 2014 Document type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo&#8217;s Medical School/BR
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