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Risk factors for Charcot foot
Nóbrega, Marta Barreto de Medeiros; Aras, Roque; Netto, Eduardo Martins; Couto, Ricardo David; Marinho, Alexandre Magno da Nóbrega; Silva, João Luís da; Colares, Víctor Nóbrega Quintas; Campelo, Priscilla Leite; Nunes, Marcos André Lima.
Affiliation
  • Nóbrega, Marta Barreto de Medeiros; Federal University of Bahia. Salvador. BR
  • Aras, Roque; Federal University of Bahia. Salvador. BR
  • Netto, Eduardo Martins; Federal University of Bahia. Salvador. BR
  • Couto, Ricardo David; Federal University of Bahia. Salvador. BR
  • Marinho, Alexandre Magno da Nóbrega; Federal University of Bahia. Salvador. BR
  • Silva, João Luís da; Federal University of Bahia. Salvador. BR
  • Colares, Víctor Nóbrega Quintas; Federal University of Bahia. Salvador. BR
  • Campelo, Priscilla Leite; Federal University of Bahia. Salvador. BR
  • Nunes, Marcos André Lima; Federal University of Bahia. Salvador. BR
Arch. endocrinol. metab. (Online) ; 59(3): 226-230, 06/2015. tab
Article in English | LILACS | ID: lil-751310
Responsible library: BR1.1
ABSTRACT
Objective Diabetes mellitus is the main cause of Charcot neuroarthropathy and is clinically classified as follows Charcot foot, acute Charcot foot (ACF) when there is inflammation, and inactive Charcot foot when inflammatory signs are absent. The aim of this study was to identify the risk factors for ACF in patients with type 2 diabetes mellitus.Materials and methods A matched case-control study was conducted to assess the factors associated with acute Charcot foot from February 2000 until September 2012. Four controls for each case were selected 47 cases of ACF and 188 controls without ACF were included. Cases and controls were matched by year of initialization of treatment. Conditional logistic regression was used to estimate matched odds ratios (ORs) and 95% confidence intervals (95% CIs).Results In multivariate analysis, patients having less than 55 years of age (adjusted OR = 4.10, 95% CI = 1.69 – 9.94), literate education age (adjusted OR = 3.73, 95% CI = 1.40 – 9.92), living alone (adjusted OR = 5.84, 95% CI = 1.49 – 22.86), previous ulceration (adjusted OR = 4.84, 95% CI = 1.62 – 14.51) were at increased risk of ACF. However, peripheral arterial disease (adjusted OR = 0.16, 95% CI = 0.05 – 0.52) of 6.25 (1.92 – 20.0) was a protective factor.Discussion The results suggest that PCA in type 2 diabetes primarily affects patients under 55 who live alone, are literate, and have a prior history of ulcers, and that peripheral arterial disease is a protective factor. Arch Endocrinol Metab. 2015;59(3)226-30.
Subject(s)


Full text: Available Collection: International databases Database: LILACS Main subject: Arthropathy, Neurogenic / Diabetic Foot / Diabetes Mellitus, Type 2 / Diabetic Neuropathies Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Arch. endocrinol. metab. (Online) Journal subject: Endocrinology / Metabolism Year: 2015 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Bahia/BR

Full text: Available Collection: International databases Database: LILACS Main subject: Arthropathy, Neurogenic / Diabetic Foot / Diabetes Mellitus, Type 2 / Diabetic Neuropathies Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Arch. endocrinol. metab. (Online) Journal subject: Endocrinology / Metabolism Year: 2015 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Bahia/BR
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