Exploring the environmental diversity of kinetoplastid flagellates in the high-throughput DNA sequencing era
Mem. Inst. Oswaldo Cruz
; 110(8): 956-965, Dec. 2015. graf
Article
in English
| LILACS
| ID: lil-769828
Responsible library:
BR1.1
ABSTRACT
The class Kinetoplastea encompasses both free-living and parasitic species from a wide range of hosts. Several representatives of this group are responsible for severe human diseases and for economic losses in agriculture and livestock. While this group encompasses over 30 genera, most of the available information has been derived from the vertebrate pathogenic genera Leishmaniaand Trypanosoma. Recent studies of the previously neglected groups of Kinetoplastea indicated that the actual diversity is much higher than previously thought. This article discusses the known segment of kinetoplastid diversity and how gene-directed Sanger sequencing and next-generation sequencing methods can help to deepen our knowledge of these interesting protists.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
Health problem:
Target 3.9: Reduce the amount of deaths produced by dangerous chemicals and the pollution of the air, water and soil
/
Neglected Diseases
Database:
LILACS
Main subject:
Phylogeny
/
DNA, Protozoan
/
RNA, Protozoan
/
Kinetoplastida
/
Biodiversity
/
High-Throughput Nucleotide Sequencing
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2015
Document type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação Oswaldo Cruz/BR