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Importancia epidemiológica del diagnóstico temprano en el manejo de sífilis gestacional y congénita, falla terapéutica del tratamiento secundaria a demora en el diagnóstico / Epidemiological importance of early diagnosis in the management of gestational and congenital syphilis, treatment failure secondary to delay in diagnosis
Corrales, Silvia Catalina.
Affiliation
  • Corrales, Silvia Catalina; s.af
Rev. salud bosque ; 3(2): 43-48, 2013. tab
Article in Spanish | LILACS | ID: lil-772952
Responsible library: CO185.1
RESUMEN
La sífilis, enfermedad legendaria, tiene formas asintomáticas y sintomáticas; sus formas de presentación son diversas y dependen de la localización y la extensión de las lesiones. Cuando se presenta en la mujer embarazada se clasifica como sífilis gestacional, con alto impacto en salud pública y con consecuencias graves, como aborto, mortinato o parto prematuro con producto enfermo. La recomendación actual del tratamiento en gestantes es la penicilina G benzatínica, 2,4 millones de unidades en dosis única o hasta 7,2 millones de unidades en tres dosis con intervalos de una semana. La evidencia hasta el momento en mujeres gestantes que presentan sífilis latente con neurosífilis o sin ella, tratadas con penicilina, ha mostrado falla terapéutica sin importar qué esquema se prescriba, esto debido a múltiples eventos tanto técnicos como de acceso. En la revisión del caso clínico de una paciente de 29 años de edad, negativa para VIH, primípara y con abandono del control prenatal, con embarazo de 29 semanas en el momento del diagnóstico de sífilis gestacional; se evidenció falla terapéutica con penicilina G benzatínica, secundaria a la falta de controles prenatales tempranos con retraso en el diagnóstico. Se identificó en el posparto, con niveles de serología reactivos y producto con sífilis gestacional.
ABSTRACT
Syphilis, legendary, has forms of asymptomatic and symptomatic; their presentations are diverse and depend on the location and extent of injuries. When it occurs in pregnant women it is classified as gestational syphilis, with high impact on public health and serious consequences, such as abortion, stillbirth or premature birth with diseased product. The current recommendation of treatment in pregnant women is penicillin G benzathine, 2.4 million units in a single dose or up to 7.2 million units in three doses at intervals of one week. The evidence so far in pregnant women with latent syphilis neurosyphilis or wrongly, treated with penicillin, has shown therapeutic failure no matter what scheme are prescribed, due to multiple events both technical access. In the review of the clinical case of a 29-year-old, negative for HIV in her first gestation and abandonment of antenatal care, with 29 week pregnancy at the time of diagnosis, gestational syphilis; evidenced therapeutic failure with penicillin G benzathine, secondary to lack of early prenatal with delay in diagnosis. It was identified in the post-partum, with levels of serology reagents and product with congenital syphilis.
Subject(s)

Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being Health problem: Goal 9: Noncommunicable diseases and mental health / Target 3.3: End transmission of communicable diseases Database: LILACS Main subject: Pregnancy Complications, Infectious / Prenatal Diagnosis / Syphilis, Congenital / Health Profile Type of study: Diagnostic study / Practice guideline / Prognostic study / Screening study / Systematic review Limits: Adult / Female / Humans / Pregnancy Language: Spanish Journal: Rev. salud bosque Journal subject: Medicine Year: 2013 Document type: Article
Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being Health problem: Goal 9: Noncommunicable diseases and mental health / Target 3.3: End transmission of communicable diseases Database: LILACS Main subject: Pregnancy Complications, Infectious / Prenatal Diagnosis / Syphilis, Congenital / Health Profile Type of study: Diagnostic study / Practice guideline / Prognostic study / Screening study / Systematic review Limits: Adult / Female / Humans / Pregnancy Language: Spanish Journal: Rev. salud bosque Journal subject: Medicine Year: 2013 Document type: Article
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