Crack-cocaine dependence and aging: effects on working memory
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
; 38(1): 58-60, Jan.-Mar. 2016. tab
Article
in En
| LILACS
| ID: lil-776497
Responsible library:
BR1.1
ABSTRACT
Objective:
To compare the working memory (WM) performance of young adult crack-cocaine dependent users, healthy older adults, and a control group of healthy young adults.Methods:
A total of 77 female participants took part in this study 26 young adult crack-cocaine dependent users (CRK), 19 healthy older adults (HO), and 32 healthy younger adults (HC). All participants completed the N-back verbal task.Results:
A multivariate analysis of covariance was performed. The model included education, income, and medication use as covariates. A group effect (F6,140 = 7.192, p < 0.001) was found. Post-hoc analyses showed that the performance of the CRK and HO groups was reduced compared to the HC group in two N-back conditions. No differences between the HO and CRK groups on WM performance were found.Conclusions:
CRK participants perform similar to HO participants on a WM task, despite the well-known effects of age on WM and the young age of CRK. These data point to a possible parallel between cognitive declines associated with crack use and developmental aging.Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Aging
/
Crack Cocaine
/
Cocaine-Related Disorders
/
Memory, Short-Term
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
Language:
En
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
PSIQUIATRIA
Year:
2016
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil