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Treatment of fistula-in-ano with cyanoacrylate glue with and without prior seton placement in rats
Romero, Gustavo Tominaga; Santos, Carlos Henrique Marques dos; Cassino, Pedro Carvalho; Odashiro, Maçanori; Seno, Gisele Zocoller; Aléssio, Gabriela Flávia.
Affiliation
  • Romero, Gustavo Tominaga; Universidade Federal do Mato Grosso do Sul. Department of Surgery. BR
  • Santos, Carlos Henrique Marques dos; Universidade Federal do Mato Grosso do Sul. Department of Surgery. BR
  • Cassino, Pedro Carvalho; Universidade Federal do Mato Grosso do Sul. Department of Surgery. BR
  • Odashiro, Maçanori; Universidade Federal do Mato Grosso do Sul. Department of Surgery. BR
  • Seno, Gisele Zocoller; Universidade Federal do Mato Grosso do Sul. Department of Surgery. BR
  • Aléssio, Gabriela Flávia; Universidade Federal do Mato Grosso do Sul. Department of Surgery. BR
Acta cir. bras ; 31(6): 377-381, graf
Article in English | LILACS | ID: lil-785017
Responsible library: BR1.1
ABSTRACT
ABSTRACT

PURPOSE:

To evaluate the efficacy of ethyl-cyanoacrylate in the treatment of fístula-in-ano in rats with and without prior seton placement.

METHODS:

Thirty rats Wistar with fístula-in-ano produced surgically, distributed in three groups group A (ethyl-cyanoacrylate) - treated by application of ethyl-cyanoacrylate into fístula tract; group B (seton + ethyl-cyanoacrylate) - seton placement followed by application of ethyl-cyanoacrylate into fístula tract, 30 days later; group C (control) - no treatment. After 60 days the animals were submited to euthanasia and the specimens were analyzed by pathologist. The results were analyzed by Chi-square test with significant value of p<0.05.

RESULTS:

One animal of group B died. Were found tracts fully healed 7, 5 and 2, in groups A, B and C, respectivelly. There was a statistically significant difference between groups A and C (p=0.02). When joined all animals treated with glue (A + B) compared to group C there was also statistically significant difference (p=0.02).

CONCLUSIONS:

The use of ethyl-cyanoacrylate glue was effective in closing anal fistulae in rats. There was no advantage in the prior application of seton.
Subject(s)


Full text: Available Collection: International databases Database: LILACS Main subject: Tissue Adhesives / Drainage / Rectal Fistula / Cyanoacrylates Limits: Animals Language: English Journal: Acta cir. bras Journal subject: CIRURGIA GERAL / Procedimentos Cir£rgicos Operat¢rios Year: 2016 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Mato Grosso do Sul/BR

Full text: Available Collection: International databases Database: LILACS Main subject: Tissue Adhesives / Drainage / Rectal Fistula / Cyanoacrylates Limits: Animals Language: English Journal: Acta cir. bras Journal subject: CIRURGIA GERAL / Procedimentos Cir£rgicos Operat¢rios Year: 2016 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Mato Grosso do Sul/BR
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