Effect of Chlorhexidine Gel in Mentally Handicapped Children highly Infected with Streptococcus Mutans
Pesqui. bras. odontopediatria clín. integr
; 15(1): 49-55, 2015. tab, graf
Article
in English
| LILACS
| ID: lil-796349
Responsible library:
BR1264.1
ABSTRACT
Objective:
To evaluate the effect of 1% chlorhexidine (CHX) gel on mentally handicapped children (n=11) highly infected with Streptococcus mutans (SM) and evaluate the re-colonization time of this bacterium after the treatment period.. Material andMethods:
Before CHX treatment, saliva samples were collected to establish baseline saliva SM levels. CHX gel was daily applied for 5 min, for 7 consecutive days. Saliva samples were then collected after 7, 30, 60, 90 and 120 days to evaluate SM oral re-colonization. Data were analyzed by the Wilcoxon test (α=0.05).Results:
When compared to baseline (5.7 / 3.0 x 105), the collection performed 7 days after CHX treatment (0.06 / 0.2 x 105) showed a significant reduction (P <0.05) in SM saliva levels (mean / s.d., CFU ml-1). In subsequent collections, a gradual SM re-colonization was observed, and after 60 days of treatment, the levels of this bacterium (0.8 / 0.9 x 105) no longer statistically differed from SM levels considered high risk to caries (105) (P> 0.05).Conclusion:
Treatment with CHX gel for 7 days was effective in reducing the SM levels of mentally handicapped children and should be repeated after 60 days to control the risk of caries in these children...
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Saliva
/
Streptococcus mutans
/
Chlorhexidine
/
Persons with Mental Disabilities
/
Dental Caries
/
Gels
Type of study:
Controlled clinical trial
/
Etiology study
/
Observational study
/
Risk factors
Limits:
Child
/
Female
/
Humans
/
Male
Language:
English
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
Dentistry
Year:
2015
Document type:
Article