Reversal of GATA-6 downregulation promotes smooth muscle differentiation and inhibits intimal hyperplasia in balloon-injured rat carotid artery.

Mano, T; Luo, Z; Malendowicz, S L; Evans, T; Walsh, K

Mano, T; Luo, Z; Malendowicz, S L; Evans, T; Walsh, K.

Affiliation

Mano T; Division of Cardiovascular Research, St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Mass. 02135, USA.

Circ Res ; 84(6): 647-54, 1999 Apr 02.

Article in En | MEDLINE | ID: mdl-10189352

Subject(s)

Carotid Artery Diseases/prevention & control; Catheterization/adverse effects; DNA-Binding Proteins/physiology; Down-Regulation; Muscle, Smooth, Vascular/cytology; Transcription Factors/physiology; Tunica Intima/pathology; Adenoviridae/genetics; Animals; Carotid Artery Diseases/metabolism; Carotid Artery Diseases/pathology; Cell Differentiation; DNA/metabolism; DNA, Complementary/biosynthesis; DNA-Binding Proteins/genetics; Down-Regulation/genetics; GATA6 Transcription Factor; Genetic Vectors/chemical synthesis; Genetic Vectors/chemistry; Hyperplasia; Male; Neovascularization, Pathologic/pathology; Neovascularization, Pathologic/prevention & control; Protein Binding/genetics; Rats; Rats, Sprague-Dawley; Transcription Factors/genetics; Virus Replication/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Catheterization / Carotid Artery Diseases / Down-Regulation / Tunica Intima / DNA-Binding Proteins / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: Circ Res Year: 1999 Document type: Article Affiliation country: United States Country of publication: United States

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