Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells.

Yoon, J W; Yoon, C S; Lim, H W; Huang, Q Q; Kang, Y; Pyun, K H; Hirasawa, K; Sherwin, R S; Jun, H S

Yoon, J W; Yoon, C S; Lim, H W; Huang, Q Q; Kang, Y; Pyun, K H; Hirasawa, K; Sherwin, R S; Jun, H S.

Affiliation

Yoon JW; Laboratory of Viral and Immunopathogenesis of Diabetes, Julia McFarlane Diabetes Research Centre, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada. yoon@ucalgary.edu

Science ; 284(5417): 1183-7, 1999 May 14.

Article in En | MEDLINE | ID: mdl-10325232

Subject(s)

Autoantigens/immunology; Diabetes Mellitus, Type 1/enzymology; Diabetes Mellitus, Type 1/immunology; Glutamate Decarboxylase/immunology; Islets of Langerhans/enzymology; Adoptive Transfer; Animals; Autoantigens/genetics; Autoantigens/physiology; Autoimmunity; DNA, Antisense; Diabetes Mellitus, Type 1/pathology; Female; Gene Expression; Glutamate Decarboxylase/genetics; Glutamate Decarboxylase/physiology; Insulin/blood; Insulin/metabolism; Islets of Langerhans/immunology; Islets of Langerhans/metabolism; Islets of Langerhans/pathology; Islets of Langerhans Transplantation; Lymphocyte Activation; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; T-Lymphocytes/immunology; Transgenes

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Autoantigens / Islets of Langerhans / Diabetes Mellitus, Type 1 / Glutamate Decarboxylase Limits: Animals Language: En Journal: Science Year: 1999 Document type: Article Affiliation country: Canada Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links