SOS-dependent A-->G transitions induced by hydroxyl radical generating system hypoxanthine/xanthine oxidase/Fe3+/EDTA are accompanied by the increase of Fapy-adenine content in M13 mp18 phage DNA.

Graziewicz, M A; Zastawny, T H; Olinski, R; Tudek, B

Graziewicz, M A; Zastawny, T H; Olinski, R; Tudek, B.

Affiliation

Graziewicz MA; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.

Mutat Res ; 434(1): 41-52, 1999 May 14.

Article in En | MEDLINE | ID: mdl-10377947

Subject(s)

Bacteriophage M13/drug effects; DNA, Viral/drug effects; Hydroxyl Radical/adverse effects; Pyrimidines/metabolism; SOS Response, Genetics/physiology; Bacteriophage M13/genetics; Bacteriophage M13/growth & development; Base Sequence; DNA Damage; DNA, Single-Stranded/drug effects; DNA, Single-Stranded/genetics; DNA, Viral/metabolism; Edetic Acid/pharmacology; Ferric Compounds/pharmacology; Genes, Viral/genetics; Hydroxyl Radical/metabolism; Hypoxanthine/metabolism; Molecular Sequence Data; Mutagenesis; Mutation; Oxidative Stress; Point Mutation; Pyrimidines/chemistry; Xanthine Oxidase/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / SOS Response, Genetics / DNA, Viral / Bacteriophage M13 / Hydroxyl Radical Language: En Journal: Mutat Res Year: 1999 Document type: Article Affiliation country: Poland Country of publication: Netherlands

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