Enhancement by IL-12 of the cytolytic T lymphocyte (CTL) response of mice immunized with tumor-specific peptides in an adjuvant containing QS21 and MPL.

Silla, S; Fallarino, F; Boon, T; Uyttenhove, C

Silla, S; Fallarino, F; Boon, T; Uyttenhove, C.

Affiliation

Silla S; Ludwig Institute for Cancer Research, Brussels Branch, 74 Avenue Hippocrate-UCL 74.59, B-1200 Brussels, Belgium.

Eur Cytokine Netw ; 10(2): 181-90, 1999 Jun.

Article in En | MEDLINE | ID: mdl-10400824

Subject(s)

Adjuvants, Immunologic; Antigens, Neoplasm/immunology; Cancer Vaccines/immunology; Histocompatibility Antigens/immunology; Interleukin-12/pharmacology; Lipid A/analogs & derivatives; Peptide Fragments/immunology; Saponins/immunology; T-Lymphocytes, Cytotoxic/drug effects; Animals; Cancer Vaccines/administration & dosage; Cytotoxicity Tests, Immunologic; Drug Synergism; Ear, External; Female; H-2 Antigens/immunology; Hindlimb; Immunotherapy, Active; Injections, Subcutaneous; Interferon-gamma/biosynthesis; Interleukin-12/administration & dosage; Lipid A/immunology; Lymphocyte Activation; Mast-Cell Sarcoma/genetics; Mast-Cell Sarcoma/immunology; Mast-Cell Sarcoma/pathology; Mice; Mice, Inbred DBA; Organ Specificity; Specific Pathogen-Free Organisms; T-Lymphocytes, Cytotoxic/immunology; Tail; Tumor Cells, Cultured

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Saponins / T-Lymphocytes, Cytotoxic / Adjuvants, Immunologic / Interleukin-12 / Cancer Vaccines / Histocompatibility Antigens / Lipid A / Antigens, Neoplasm Type of study: Guideline / Prognostic_studies Limits: Animals Language: En Journal: Eur Cytokine Netw Journal subject: ALERGIA E IMUNOLOGIA Year: 1999 Document type: Article Affiliation country: Belgium Country of publication: France

Search on Google

Add to My VHL

XML

PubMed Links