Synergistic activation of the prolactin promoter by vitamin D receptor and GHF-1: role of the coactivators, CREB-binding protein and steroid hormone receptor coactivator-1 (SRC-1).

Castillo, A I; Jimenez-Lara, A M; Tolon, R M; Aranda, A

Castillo, A I; Jimenez-Lara, A M; Tolon, R M; Aranda, A.

Affiliation

Castillo AI; Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.

Mol Endocrinol ; 13(7): 1141-54, 1999 Jul.

Article in En | MEDLINE | ID: mdl-10406465

Subject(s)

DNA-Binding Proteins/metabolism; Nuclear Proteins/metabolism; Prolactin/genetics; Receptors, Calcitriol/metabolism; Trans-Activators/metabolism; Transcription Factors/metabolism; Animals; Base Sequence; CREB-Binding Protein; DNA-Binding Proteins/genetics; Dimerization; Furylfuramide/metabolism; HeLa Cells/metabolism; Histone Acetyltransferases; Humans; Molecular Sequence Data; Mutation; Nuclear Receptor Coactivator 1; Pituitary Neoplasms/genetics; Pituitary Neoplasms/metabolism; Prolactin/metabolism; Promoter Regions, Genetic; Rats; Receptors, Calcitriol/genetics; Receptors, Retinoic Acid/chemistry; Receptors, Retinoic Acid/metabolism; Response Elements/genetics; Retinoid X Receptors; Transcription Factor Pit-1; Transcription Factors/chemistry; Transcription Factors/genetics; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Vitamin D/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Prolactin / Transcription Factors / Nuclear Proteins / Trans-Activators / Receptors, Calcitriol / DNA-Binding Proteins Limits: Animals / Humans Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 1999 Document type: Article Affiliation country: Spain

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