mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop.

Kume, K; Zylka, M J; Sriram, S; Shearman, L P; Weaver, D R; Jin, X; Maywood, E S; Hastings, M H; Reppert, S M

Kume, K; Zylka, M J; Sriram, S; Shearman, L P; Weaver, D R; Jin, X; Maywood, E S; Hastings, M H; Reppert, S M.

Affiliation

Kume K; Laboratory of Developmental Chronobiology, Pediatric Service, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.

Cell ; 98(2): 193-205, 1999 Jul 23.

Article in En | MEDLINE | ID: mdl-10428031

Subject(s)

Biological Clocks/physiology; Drosophila Proteins; Eye Proteins; Flavoproteins/genetics; Photoreceptor Cells, Invertebrate; 3T3 Cells; ARNTL Transcription Factors; Animals; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; CLOCK Proteins; COS Cells; Cell Cycle Proteins; Cell Nucleus/metabolism; Cloning, Molecular; Cryptochromes; Feedback/physiology; Female; Flavoproteins/analysis; Flavoproteins/metabolism; Gene Expression/physiology; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Molecular Sequence Data; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Period Circadian Proteins; RNA, Messenger/metabolism; Receptors, G-Protein-Coupled; Suprachiasmatic Nucleus/chemistry; Suprachiasmatic Nucleus/metabolism; Trans-Activators/genetics; Trans-Activators/metabolism; Transcription Factors/genetics; Transcription Factors/metabolism; Transcription, Genetic/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Biological Clocks / Photoreceptor Cells, Invertebrate / Drosophila Proteins / Eye Proteins / Flavoproteins Language: En Journal: Cell Year: 1999 Document type: Article Affiliation country: United States Country of publication: United States

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