Age-related alterations of somatic hypermutation and CDR3 lengths in human Vkappa4-expressing B lymphocytes.

Troutaud, D; Drouet, M; Decourt, C; Le Morvan, C; Cogné, M

Troutaud, D; Drouet, M; Decourt, C; Le Morvan, C; Cogné, M.

Affiliation

Troutaud D; Faculté des Sciences, Laboratoire d'Immunologie et d'Immunogénétique, Limoges, France.

Immunology ; 97(2): 197-203, 1999 Jun.

Article in En | MEDLINE | ID: mdl-10447732

Subject(s)

Aging/immunology; B-Lymphocyte Subsets/immunology; Immunoglobulin Variable Region/genetics; Immunoglobulin kappa-Chains/metabolism; Mutation/immunology; Adult; Aged; Aged, 80 and over; Base Sequence; Genetic Variation; Humans; Immunoglobulin J-Chains/genetics; Immunoglobulin Variable Region/immunology; Immunoglobulin kappa-Chains/genetics; Middle Aged; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Immunoglobulin Variable Region / B-Lymphocyte Subsets / Immunoglobulin kappa-Chains / Mutation Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Humans / Middle aged Language: En Journal: Immunology Year: 1999 Document type: Article Affiliation country: France

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