Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-Pyrimidinyl)- methyl-3-(2-Chloroethyl)-3-nitrosourea resistance by antisense RNA.

Ji, S P; Zhang, Y P

Ji, S P; Zhang, Y P.

Affiliation

Ji SP; Institute of Blood Transfusion Medicine, Beijing, China.

Cancer Detect Prev ; 23(5): 422-7, 1999.

Article in En | MEDLINE | ID: mdl-10468895

Subject(s)

Nimustine/antagonists & inhibitors; O(6)-Methylguanine-DNA Methyltransferase/metabolism; RNA, Antisense/pharmacology; Animals; Dose-Response Relationship, Drug; Genetic Vectors; HeLa Cells; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Models, Genetic; Neoplasms, Experimental/drug therapy; Neoplasms, Experimental/pathology; O(6)-Methylguanine-DNA Methyltransferase/genetics; Phenotype; Plasmids; Retroviridae/genetics; Time Factors; Transduction, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Nimustine / RNA, Antisense / O(6)-Methylguanine-DNA Methyltransferase Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Detect Prev Year: 1999 Document type: Article Affiliation country: China Country of publication: United kingdom

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