Preexposure to drug administration context blocks the development of tolerance to sedative effects of diazepam.

Marin, R H; Pérez, M F; Duero, D G; Ramirez, O A

Marin, R H; Pérez, M F; Duero, D G; Ramirez, O A.

Affiliation

Marin RH; Cátedra de Química Biológica Facultad Ciencias Exactas Físicas y Naturales, Universidad Nacional de Córdoba, Argentina.

Pharmacol Biochem Behav ; 64(3): 473-7, 1999 Nov.

Article in En | MEDLINE | ID: mdl-10548258

Subject(s)

Diazepam/pharmacology; Hypnotics and Sedatives/pharmacology; Animals; Conditioning, Operant/drug effects; Drug Tolerance; Electric Stimulation; Electrophysiology; Hippocampus/drug effects; Learning/drug effects; Long-Term Potentiation/drug effects; Male; Memory/drug effects; Motor Activity/drug effects; Neuronal Plasticity/drug effects; Rats; Rats, Wistar; Synapses/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Diazepam / Hypnotics and Sedatives Limits: Animals Language: En Journal: Pharmacol Biochem Behav Year: 1999 Document type: Article Affiliation country: Argentina

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