Suppression of mouse hepatocyte apoptosis by peroxisome proliferators: role of PPARalpha and TNFalpha.

Hasmall, S C; James, N H; Macdonald, N; Gonzalez, F J; Peters, J M; Roberts, R A

Hasmall, S C; James, N H; Macdonald, N; Gonzalez, F J; Peters, J M; Roberts, R A.

Affiliation

Hasmall SC; AstraZeneca Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, UK. sue.hasmall@ctl.astrazeneca.com

Mutat Res ; 448(2): 193-200, 2000 Mar 17.

Article in En | MEDLINE | ID: mdl-10725472

Subject(s)

Apoptosis/drug effects; Liver/drug effects; Nafenopin/toxicity; Peroxisome Proliferators/toxicity; Receptors, Cytoplasmic and Nuclear/physiology; Transcription Factors/physiology; Tumor Necrosis Factor-alpha/physiology; Animals; DNA/biosynthesis; DNA/drug effects; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Peroxisomes/drug effects; Phenobarbital/pharmacology; Receptors, Cytoplasmic and Nuclear/genetics; Transcription Factors/genetics; Tumor Necrosis Factor-alpha/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Tumor Necrosis Factor-alpha / Apoptosis / Receptors, Cytoplasmic and Nuclear / Peroxisome Proliferators / Liver / Nafenopin Limits: Animals Language: En Journal: Mutat Res Year: 2000 Document type: Article Affiliation country: United kingdom Country of publication: Netherlands

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