Free cholesterol loading of macrophages induces apoptosis involving the fas pathway.

Yao, P M; Tabas, I

Yao, P M; Tabas, I.

Affiliation

Yao PM; Departments of Medicine and Anatomy and Cell Biology, Columbia University, New York, New York 10032, USA.

J Biol Chem ; 275(31): 23807-13, 2000 Aug 04.

Article in En | MEDLINE | ID: mdl-10791964

Subject(s)

Apoptosis; Cholesterol/metabolism; Macrophages, Peritoneal/metabolism; fas Receptor/metabolism; Animals; Annexin A5; Arteriosclerosis/etiology; Caspase Inhibitors; Coloring Agents; Cysteine Proteinase Inhibitors/pharmacology; Fas Ligand Protein; Foam Cells; In Situ Nick-End Labeling; Ligands; Membrane Glycoproteins/metabolism; Mice; Mice, Inbred C57BL; Models, Biological; Oligopeptides/pharmacology; Propidium; Signal Transduction

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Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Apoptosis / Macrophages, Peritoneal / Fas Receptor Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2000 Document type: Article Affiliation country: United States Country of publication: United States

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