Impaired nitric oxide-mediated vasodilation in transgenic sickle mouse.

Kaul, D K; Liu, X D; Fabry, M E; Nagel, R L

Kaul, D K; Liu, X D; Fabry, M E; Nagel, R L.

Affiliation

Kaul DK; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. kaul@aecom.yu.edu

Am J Physiol Heart Circ Physiol ; 278(6): H1799-806, 2000 Jun.

Article in En | MEDLINE | ID: mdl-10843875

Subject(s)

Anemia, Sickle Cell/physiopathology; Nitric Oxide/physiology; Vasodilation; Animals; Arginine/pharmacology; Blood Pressure/drug effects; Colforsin/pharmacology; Cyclooxygenase Inhibitors/pharmacology; Endothelium, Vascular/physiology; Enzyme Inhibitors/pharmacology; Hemoglobin, Sickle/analysis; Hemoglobin, Sickle/genetics; Humans; Indomethacin/pharmacology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic/genetics; Microcirculation/drug effects; NG-Nitroarginine Methyl Ester/pharmacology; Nitric Oxide Synthase/metabolism; Vasodilator Agents/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Vasodilation / Anemia, Sickle Cell / Nitric Oxide Limits: Animals / Humans / Male Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2000 Document type: Article Affiliation country: United States

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