Retroviral expression of the hepatitis B virus x gene promotes liver cell susceptibility to carcinogen-induced site specific mutagenesis.

Sohn, S; Jaitovitch-Groisman, I; Benlimame, N; Galipeau, J; Batist, G; Alaoui-Jamali, M A

Sohn, S; Jaitovitch-Groisman, I; Benlimame, N; Galipeau, J; Batist, G; Alaoui-Jamali, M A.

Affiliation

Sohn S; Departments of Medicine, Oncology, Pharmacology and Therapeutics, and Center for Translational Research in Cancer, Lady Davis Institute for Medical Research of the Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

Mutat Res ; 460(1): 17-28, 2000 Jun 30.

Article in En | MEDLINE | ID: mdl-10856831

Subject(s)

Carcinogens/toxicity; Hepatitis B virus; Liver/drug effects; Liver/metabolism; Mutagenesis, Site-Directed/drug effects; Trans-Activators/metabolism; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide/metabolism; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide/toxicity; Aflatoxin B1/analogs & derivatives; Aflatoxin B1/metabolism; Aflatoxin B1/toxicity; Apoptosis/drug effects; Carcinogens/metabolism; Cell Cycle/drug effects; Cell Line; Codon/genetics; DNA Mutational Analysis; Disease Susceptibility; Genes, p53/genetics; Genetic Vectors/genetics; Hepatitis B virus/genetics; Hepatitis B virus/pathogenicity; Humans; Liver/cytology; Liver/virology; Mutagens/metabolism; Mutagens/toxicity; Mutation/genetics; Polymerase Chain Reaction; Trans-Activators/genetics; Transduction, Genetic; Viral Regulatory and Accessory Proteins

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Collection: 01-internacional Database: MEDLINE Main subject: Carcinogens / Trans-Activators / Hepatitis B virus / Mutagenesis, Site-Directed / Liver Limits: Humans Language: En Journal: Mutat Res Year: 2000 Document type: Article Affiliation country: Canada Country of publication: Netherlands

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