Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia.

Lavau, C; Du, C; Thirman, M; Zeleznik-Le, N

Lavau, C; Du, C; Thirman, M; Zeleznik-Le, N.

Affiliation

Lavau C; Systemix, Inc., 3155 Porter Drive, Palo Alto, CA 94304, USA. catlav@jupiter.chu-stlouis.fr

EMBO J ; 19(17): 4655-64, 2000 Sep 01.

Article in En | MEDLINE | ID: mdl-10970858

Subject(s)

DNA-Binding Proteins/metabolism; Leukemia, Myeloid/pathology; Myelodysplastic Syndromes/metabolism; Nuclear Proteins/metabolism; Proto-Oncogenes; Recombinant Fusion Proteins/metabolism; Trans-Activators/metabolism; Transcription Factors; Animals; Base Sequence; CREB-Binding Protein; DNA Primers; DNA-Binding Proteins/genetics; Histone-Lysine N-Methyltransferase; Mice; Myelodysplastic Syndromes/pathology; Myeloid-Lymphoid Leukemia Protein; Nuclear Proteins/genetics; Recombinant Fusion Proteins/genetics; Trans-Activators/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Myelodysplastic Syndromes / Recombinant Fusion Proteins / Proto-Oncogenes / Nuclear Proteins / Leukemia, Myeloid / Trans-Activators / DNA-Binding Proteins Limits: Animals Language: En Journal: EMBO J Year: 2000 Document type: Article Affiliation country: United States Country of publication: United kingdom

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