A novel class of inhibitors for human and rat steroid 5alpha-reductases: synthesis and biological evaluation of indoline and aniline derivatives. III.

Igarashi, S; Inami, H; Hara, H; Koutoku, H; Oritani, H; Mase, T

Igarashi, S; Inami, H; Hara, H; Koutoku, H; Oritani, H; Mase, T.

Affiliation

Igarashi S; Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co, Ltd, Tsukuba, Ibaraki, Japan. igara@yamanouchi.co.jp

Chem Pharm Bull (Tokyo) ; 48(11): 1689-97, 2000 Nov.

Article in En | MEDLINE | ID: mdl-11086897

Subject(s)

5-alpha Reductase Inhibitors; Aniline Compounds/chemical synthesis; Enzyme Inhibitors/chemical synthesis; Indoles/chemical synthesis; Aniline Compounds/pharmacology; Animals; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors/pharmacology; Humans; Indoles/pharmacology; Male; Prostate/drug effects; Prostate/enzymology; Rats; Rats, Sprague-Dawley; Rats, Wistar

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Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Inhibitors / 5-alpha Reductase Inhibitors / Indoles / Aniline Compounds Limits: Animals / Humans / Male Language: En Journal: Chem Pharm Bull (Tokyo) Year: 2000 Document type: Article Affiliation country: Japan

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