Xanthine oxidase released from reperfused hind limbs mediate kupffer cell activation, neutrophil sequestration, and hepatic oxidative stress in rats subjected to tourniquet shock.

Vega, V L; Mardones, L; Maldonado, M; Nicovani, S; Manríquez, V; Roa, J; Ward, P H

Vega, V L; Mardones, L; Maldonado, M; Nicovani, S; Manríquez, V; Roa, J; Ward, P H.

Affiliation

Vega VL; Departamento de Fisiopatología, Universidad de Concepción, Chile.

Shock ; 14(5): 565-71, 2000 Nov.

Article in En | MEDLINE | ID: mdl-11092691

Subject(s)

Hindlimb/blood supply; Ischemia/physiopathology; Kupffer Cells/physiology; Liver/physiopathology; Neutrophils/physiology; Oxidative Stress/physiology; Shock/physiopathology; Xanthine Oxidase/metabolism; Alanine Transaminase/blood; Animals; Female; L-Lactate Dehydrogenase/blood; Liver/physiology; Macrophage Activation; Muscle, Skeletal/physiopathology; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors; Tourniquets; Xanthine Dehydrogenase/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Shock / Xanthine Oxidase / Oxidative Stress / Hindlimb / Ischemia / Kupffer Cells / Liver / Neutrophils Type of study: Prognostic_studies Limits: Animals Language: En Journal: Shock Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2000 Document type: Article Affiliation country: Chile

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