Non-ionic detergent affects the conformation of a functionally active mutant of Bcl-X(L).

Tan, Y J; Ting, A E

Tan, Y J; Ting, A E.

Affiliation

Tan YJ; Institute of Molecular and Cell Biology, 30 Medical Drive, Singapore 117609, Republic of Singapore. mcbtanyj@imcb.nus.edu.sg

Protein Eng ; 13(12): 887-92, 2000 Dec.

Article in En | MEDLINE | ID: mdl-11239089

Subject(s)

Detergents/pharmacology; Polyethylene Glycols/pharmacology; Protein Binding/physiology; Proto-Oncogene Proteins c-bcl-2/metabolism; Proto-Oncogene Proteins/metabolism; Circular Dichroism; Glutathione Transferase/metabolism; Humans; Mass Spectrometry; Mutation; Octoxynol; Precipitin Tests; Protein Biosynthesis; Protein Conformation; Recombinant Fusion Proteins/isolation & purification; Recombinant Fusion Proteins/metabolism; Transfection; bcl-2-Associated X Protein; bcl-X Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Protein Binding / Proto-Oncogene Proteins / Proto-Oncogene Proteins c-bcl-2 / Detergents Limits: Humans Language: En Journal: Protein Eng Journal subject: BIOQUIMICA / BIOTECNOLOGIA Year: 2000 Document type: Article Country of publication: United kingdom

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