Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice.

Andreassen, O A; Dedeoglu, A; Friedlich, A; Ferrante, K L; Hughes, D; Szabo, C; Beal, M F

Andreassen, O A; Dedeoglu, A; Friedlich, A; Ferrante, K L; Hughes, D; Szabo, C; Beal, M F.

Affiliation

Andreassen OA; Neurochemistry Laboratory, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

Exp Neurol ; 168(2): 419-24, 2001 Apr.

Article in En | MEDLINE | ID: mdl-11259130

Subject(s)

Amphetamines/pharmacology; Motor Skills/drug effects; Neuroprotective Agents/pharmacology; Poly(ADP-ribose) Polymerase Inhibitors; Thioctic Acid/pharmacology; Trientine/pharmacology; Amphetamines/therapeutic use; Amyotrophic Lateral Sclerosis/drug therapy; Amyotrophic Lateral Sclerosis/genetics; Animals; Female; Male; Mice; Mice, Transgenic; Motor Skills/physiology; Neuroprotective Agents/therapeutic use; Survival; Thioctic Acid/therapeutic use; Trientine/therapeutic use; Weight Loss/drug effects; Weight Loss/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Trientine / Thioctic Acid / Neuroprotective Agents / Poly(ADP-ribose) Polymerase Inhibitors / Amphetamines / Motor Skills Limits: Animals Language: En Journal: Exp Neurol Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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