Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture.

DeWitt, A E; Dong, J Y; Wiley, H S; Lauffenburger, D A

DeWitt, A E; Dong, J Y; Wiley, H S; Lauffenburger, D A.

Affiliation

DeWitt AE; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

J Cell Sci ; 114(Pt 12): 2301-13, 2001 Jun.

Article in En | MEDLINE | ID: mdl-11493669

Subject(s)

Autocrine Communication; Epidermal Growth Factor/metabolism; ErbB Receptors/metabolism; Animals; Antibodies/pharmacology; Autocrine Communication/drug effects; Breast/cytology; Breast/drug effects; Breast/metabolism; Cell Division/drug effects; Enzyme Activation/drug effects; Epidermal Growth Factor/genetics; Epithelial Cells/cytology; Epithelial Cells/drug effects; Epithelial Cells/metabolism; ErbB Receptors/antagonists & inhibitors; ErbB Receptors/genetics; Fibroblasts; Humans; Kinetics; Ligands; Mice; Models, Biological; Transfection

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Autocrine Communication / Epidermal Growth Factor / ErbB Receptors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Cell Sci Year: 2001 Document type: Article Affiliation country: United States Country of publication: United kingdom

Search on Google

Add to My VHL

XML

PubMed Links