Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers.

Dunn, S E; Simard, A R; Bassel-Duby, R; Williams, R S; Michel, R N

Dunn, S E; Simard, A R; Bassel-Duby, R; Williams, R S; Michel, R N.

Affiliation

Dunn SE; Neuromuscular Research Laboratory, Department of Chemistry and Biochemistry, Laurentian University, Sudbury, Ontario P3E 2C6, Canada.

J Biol Chem ; 276(48): 45243-54, 2001 Nov 30.

Article in En | MEDLINE | ID: mdl-11555650

Subject(s)

Calcineurin/metabolism; DNA-Binding Proteins/metabolism; Muscle Fibers, Fast-Twitch/metabolism; Muscle Fibers, Slow-Twitch/metabolism; Neurons/metabolism; Nuclear Proteins; Signal Transduction; Transcription Factors/metabolism; Animals; Blotting, Western; Cell Nucleus/metabolism; Cyclosporine/pharmacology; Enzyme Inhibitors/pharmacology; Genes, Reporter; Genotype; Green Fluorescent Proteins; Immunohistochemistry; Immunosuppressive Agents/pharmacology; Luminescent Proteins/metabolism; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; Muscles/cytology; Myogenic Regulatory Factors; NFATC Transcription Factors; Phenotype; Phosphorylation; Plasmids/metabolism; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins/metabolism; Tacrolimus/pharmacology; Time Factors; Transcription, Genetic; beta-Galactosidase/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Signal Transduction / Muscle Fibers, Slow-Twitch / Muscle Fibers, Fast-Twitch / Calcineurin / DNA-Binding Proteins / Neurons Limits: Animals Language: En Journal: J Biol Chem Year: 2001 Document type: Article Affiliation country: Canada

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