DNA topology on an increase in positive writhing number of DNA: conformation changes in the time course of cis-diamminedichloroplatinum(II)-DNA adducts.

Kobayashi, S; Nakamura, Y; Maehara, T; Hamashima, H; Sasatsu, M; Asano, K; Ohishi, Y; Tanaka, A

Kobayashi, S; Nakamura, Y; Maehara, T; Hamashima, H; Sasatsu, M; Asano, K; Ohishi, Y; Tanaka, A.

Affiliation

Kobayashi S; Department of Analytical Chemistry of Medicines, Showa Pharmaceutical University, Machida, Tokyo, Japan. kobayasi@ac.shoyaku.ac.jp

Chem Pharm Bull (Tokyo) ; 49(9): 1053-60, 2001 Sep.

Article in En | MEDLINE | ID: mdl-11558585

Subject(s)

Antineoplastic Agents/pharmacology; Cisplatin/pharmacology; DNA Adducts/chemistry; DNA/chemistry; Algorithms; Cyanides/chemistry; DNA, Superhelical/chemistry; Electrophoresis, Polyacrylamide Gel; Guanine/chemistry; Microscopy, Electron; Nucleic Acid Conformation; Platinum/chemistry; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: DNA / Cisplatin / DNA Adducts / Antineoplastic Agents Type of study: Prognostic_studies Language: En Journal: Chem Pharm Bull (Tokyo) Year: 2001 Document type: Article Affiliation country: Japan Country of publication: Japan

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