Langerhans cells and immature dendritic cells as model systems for screening of skin sensitizers.

Tuschl, H; Kovac, R

Tuschl, H; Kovac, R.

Affiliation

Tuschl H; Austrian Research Centers Seibersdorf, Department of Toxicology, A-2444 Seibersdorf, Austria. helga.tuschl@arcs.ac.at

Toxicol In Vitro ; 15(4-5): 327-31, 2001.

Article in En | MEDLINE | ID: mdl-11566557

Subject(s)

Acrolein/analogs & derivatives; Allergens/toxicity; Dendritic Cells/drug effects; Drug Evaluation, Preclinical/methods; Langerhans Cells/drug effects; Acrolein/toxicity; Animal Testing Alternatives; Antigens, CD/metabolism; Antigens, Surface/biosynthesis; B7-2 Antigen; Cells, Cultured; Dendritic Cells/cytology; Dendritic Cells/metabolism; Dinitrochlorobenzene/toxicity; Eugenol/toxicity; Flow Cytometry; Humans; Interleukin-1/biosynthesis; Langerhans Cells/cytology; Langerhans Cells/metabolism; Membrane Glycoproteins/metabolism; Models, Biological; Monocytes/cytology; Nickel/toxicity; Skin; Trinitrobenzenesulfonic Acid/toxicity; Up-Regulation

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Collection: 01-internacional Database: MEDLINE Main subject: Acrolein / Dendritic Cells / Allergens / Langerhans Cells / Drug Evaluation, Preclinical Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: Toxicol In Vitro Journal subject: TOXICOLOGIA Year: 2001 Document type: Article Affiliation country: Austria Country of publication: United kingdom

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