Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses.

Lu, L; Han, A P; Chen, J J

Lu, L; Han, A P; Chen, J J.

Affiliation

Lu L; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Mol Cell Biol ; 21(23): 7971-80, 2001 Dec.

Article in En | MEDLINE | ID: mdl-11689689

Subject(s)

Erythroid Precursor Cells/metabolism; Protein Biosynthesis/physiology; Reticulocytes/metabolism; Stress, Physiological/metabolism; eIF-2 Kinase/metabolism; Animals; Arsenites/pharmacology; Cell Separation; Cytoplasm/metabolism; Endoplasmic Reticulum/metabolism; Enzyme Activation/drug effects; Erythroid Precursor Cells/drug effects; Eukaryotic Initiation Factor-2/metabolism; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins/metabolism; HSP90 Heat-Shock Proteins/metabolism; Heat-Shock Response/physiology; Liver/cytology; Liver/drug effects; Liver/embryology; Liver/metabolism; Mice; Mice, Knockout; Osmotic Pressure; Oxidative Stress/drug effects; Oxidative Stress/physiology; Phosphorylation/drug effects; Reactive Oxygen Species/metabolism; Reticulocytes/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reticulocytes / Stress, Physiological / Protein Biosynthesis / Erythroid Precursor Cells / EIF-2 Kinase Limits: Animals Language: En Journal: Mol Cell Biol Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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