Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-kinase in 1321N1 astrocytoma cells.

Tang, Xiuwen; Batty, Ian H; Downes, C Peter

Tang, Xiuwen; Batty, Ian H; Downes, C Peter.

Affiliation

Tang X; Division of Cell Signalling, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland. x.tang@dundee.ac.uk

J Biol Chem ; 277(1): 338-44, 2002 Jan 04.

Article in En | MEDLINE | ID: mdl-11694521

Subject(s)

Astrocytoma/enzymology; Phosphatidylinositol 3-Kinases/physiology; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins/physiology; Receptor, ErbB-3/physiology; Receptors, Muscarinic/physiology; Type C Phospholipases/physiology; Astrocytoma/pathology; Calcium Signaling; Carbachol/pharmacology; Enzyme Activation; Humans; Protein Kinase C/physiology; Proto-Oncogene Proteins c-akt; Transcriptional Activation; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Type C Phospholipases / Astrocytoma / Proto-Oncogene Proteins / Receptors, Muscarinic / Protein Serine-Threonine Kinases / Phosphatidylinositol 3-Kinases / Receptor, ErbB-3 Limits: Humans Language: En Journal: J Biol Chem Year: 2002 Document type: Article Affiliation country: United kingdom Country of publication: United States

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