Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes.

Langouët, Sophie; Paehler, Axel; Welti, Dieter H; Kerriguy, Nathalie; Guillouzo, André; Turesky, Robert J

Langouët, Sophie; Paehler, Axel; Welti, Dieter H; Kerriguy, Nathalie; Guillouzo, André; Turesky, Robert J.

Affiliation

Langouët S; INSERM U456, Faculté de Pharmacie, Université de Rennes I, 35043 Rennes, France. sophie.langouet@rennes.inserm.fr

Carcinogenesis ; 23(1): 115-22, 2002 Jan.

Article in En | MEDLINE | ID: mdl-11756232

Subject(s)

Hepatocytes/metabolism; Imidazoles/metabolism; Theophylline/analogs & derivatives; Animals; Biotransformation/drug effects; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2/metabolism; Dose-Response Relationship, Drug; Hepatocytes/drug effects; Humans; Imidazoles/administration & dosage; Imidazoles/chemistry; Isoenzymes/metabolism; Magnetic Resonance Spectroscopy; Rats; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Theophylline/pharmacology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Theophylline / Hepatocytes / Imidazoles Limits: Animals / Humans Language: En Journal: Carcinogenesis Year: 2002 Document type: Article Affiliation country: France Country of publication: United kingdom

Search on Google

Add to My VHL

XML

PubMed Links