Efficient lipase-catalyzed enantioselective desymmetrization of prochiral 2,2-disubstituted 1,3-propanediols and meso 1,2-diols using 1-ethoxyvinyl 2-furoate.

Akai, Shuji; Naka, Tadaatsu; Fujita, Tetsuya; Takebe, Yasushi; Tsujino, Toshiaki; Kita, Yasuyuki

Akai, Shuji; Naka, Tadaatsu; Fujita, Tetsuya; Takebe, Yasushi; Tsujino, Toshiaki; Kita, Yasuyuki.

Affiliation

Akai S; Graduate School of Pharmaceutical Sciences, Osaka University, Yamada-oka, Suita, Osaka 565-0871, Japan.

J Org Chem ; 67(2): 411-9, 2002 Jan 25.

Article in En | MEDLINE | ID: mdl-11798311

Subject(s)

Benzoates/chemical synthesis; Candida/enzymology; Carboxylic Acids/chemical synthesis; Furans/chemistry; Lipase/metabolism; Propylene Glycols/chemistry; Propylene Glycols/chemical synthesis; Benzoates/chemistry; Carboxylic Acids/chemistry; Catalysis; Chemistry, Organic; Chromatography, High Pressure Liquid; Esters/chemical synthesis; Esters/chemistry; Kinetics; Molecular Structure; Organic Chemistry Phenomena; Stereoisomerism; Structure-Activity Relationship; Time Factors; Vinyl Compounds/chemical synthesis; Vinyl Compounds/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Propylene Glycols / Benzoates / Candida / Carboxylic Acids / Furans / Lipase Language: En Journal: J Org Chem Year: 2002 Document type: Article Affiliation country: Japan Country of publication: United States

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