Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

Sapkota, Gopal P; Boudeau, Jérôme; Deak, Maria; Kieloch, Agnieszka; Morrice, Nick; Alessi, Dario R

Sapkota, Gopal P; Boudeau, Jérôme; Deak, Maria; Kieloch, Agnieszka; Morrice, Nick; Alessi, Dario R.

Affiliation

Sapkota GP; MRC Protein Phosphorylation Unit, MSI/WTB complex, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK. g.p.sapkota@dundee.ac.uk

Biochem J ; 362(Pt 2): 481-90, 2002 Mar 01.

Article in En | MEDLINE | ID: mdl-11853558

Subject(s)

Peutz-Jeghers Syndrome/genetics; Phosphoserine/metabolism; Phosphothreonine/metabolism; Protein Serine-Threonine Kinases/genetics; AMP-Activated Protein Kinase Kinases; Amino Acid Sequence; Animals; Cell Line; Drosophila; Embryo, Mammalian; Embryo, Nonmammalian; Humans; Kidney; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases/chemistry; Protein Serine-Threonine Kinases/metabolism; Sequence Alignment; Sequence Homology, Amino Acid; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoserine / Phosphothreonine / Peutz-Jeghers Syndrome / Protein Serine-Threonine Kinases Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Biochem J Year: 2002 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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