Cell Membrane/metabolism; Gene Expression Regulation, Neoplastic; Proto-Oncogene Proteins/metabolism; 3T3 Cells; Amino Acid Motifs; Animals; COS Cells; Catalytic Domain; Cyclin D1/metabolism; Fibroblasts/metabolism; Gene Deletion; Glutathione Transferase/metabolism; Guanine Nucleotide Exchange Factors/metabolism; Guanosine Diphosphate/metabolism; Guanosine Triphosphate/metabolism; JNK Mitogen-Activated Protein Kinases; Luciferases/metabolism; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases/metabolism; Mutation; NF-kappa B/metabolism; Plasmids/metabolism; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins/metabolism; Signal Transduction; Time Factors; Transfection; cdc42 GTP-Binding Protein/metabolism; rhoA GTP-Binding Protein/metabolism