The structural motif in chondroitin sulfate for adhesion of Plasmodium falciparum-infected erythrocytes comprises disaccharide units of 4-O-sulfated and non-sulfated N-acetylgalactosamine linked to glucuronic acid.

Chai, Wengang; Beeson, James G; Lawson, Alexander M

Chai, Wengang; Beeson, James G; Lawson, Alexander M.

Affiliation

Chai W; Medical Research Council Glycosciences Laboratory, Imperial College School of Medicine, Northwick Park Hospital, Harrow, Middlesex HA1 3UJ, United Kingdom. w.chai@ic.ac.uk

J Biol Chem ; 277(25): 22438-46, 2002 Jun 21.

Article in En | MEDLINE | ID: mdl-11956186

Subject(s)

Chondroitin Sulfates/chemistry; Erythrocytes/microbiology; Plasmodium falciparum/metabolism; Acetylgalactosamine/metabolism; Amino Acid Motifs; Animals; Cell Adhesion; Chondroitin Sulfates/metabolism; Chromatography, High Pressure Liquid; Disaccharides/metabolism; Dose-Response Relationship, Drug; Erythrocytes/metabolism; Glucuronic Acid/metabolism; Hexuronic Acids/chemistry; Monosaccharides/chemistry; Oligosaccharides/chemistry; Oligosaccharides/metabolism; Polysaccharides/chemistry; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Sulfur/metabolism; Uronic Acids/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Chondroitin Sulfates / Erythrocytes Limits: Animals Language: En Journal: J Biol Chem Year: 2002 Document type: Article Affiliation country: United kingdom Country of publication: United States

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