Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain.

Su, Joseph H; Kesslak, J Patrick; Head, Elizabeth; Cotman, Carl W

Su, Joseph H; Kesslak, J Patrick; Head, Elizabeth; Cotman, Carl W.

Affiliation

Su JH; Institute for Brain Aging and Dementia, University of California at Irvine, 92697-4540, USA. josephsu@uci.edu

Acta Neuropathol ; 104(1): 1-6, 2002 Jul.

Article in En | MEDLINE | ID: mdl-12070657

Subject(s)

Alzheimer Disease/pathology; Amyloid beta-Protein Precursor/metabolism; Brain/pathology; Caspases/metabolism; Down Syndrome/pathology; Aged; Alzheimer Disease/metabolism; Brain/metabolism; Caspase 3; Caspase 8; Caspase 9; Cytoplasm/metabolism; Cytoplasm/pathology; Down Syndrome/metabolism; Humans; Immunohistochemistry; Neurons/metabolism; Neurons/pathology; Vacuoles/metabolism; Vacuoles/pathology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Brain / Amyloid beta-Protein Precursor / Down Syndrome / Caspases / Alzheimer Disease Limits: Aged / Humans Language: En Journal: Acta Neuropathol Year: 2002 Document type: Article Affiliation country: United States Country of publication: Germany

Search on Google

Add to My VHL

XML

PubMed Links