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[Relationship between the expression of bcl-2 apoptosis and acute myelogenous leukemia prognosis].
Liu, J; Cao, P; Qi, Z H.
Affiliation
  • Liu J; Department of Hematology, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Hunan Yi Ke Da Xue Xue Bao ; 25(3): 265-6, 2000 Jun 28.
Article in Zh | MEDLINE | ID: mdl-12212162
In order to check the anti-apoptosis gene bcl-2 protein expression in 58 AML patients we used the immunohistochemical method, and analyse the relationship between bcl-2 protein and prognosis of AML. The result showed that the high expression of bcl-2 protein was related to poor clinical prognosis of AML. This shows that the expression of bcl-2 gene can serve as an index for the prognosis of AML.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Proto-Oncogene Proteins c-bcl-2 Type of study: Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: Zh Journal: Hunan Yi Ke Da Xue Xue Bao Journal subject: MEDICINA Year: 2000 Document type: Article Country of publication: China
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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Proto-Oncogene Proteins c-bcl-2 Type of study: Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: Zh Journal: Hunan Yi Ke Da Xue Xue Bao Journal subject: MEDICINA Year: 2000 Document type: Article Country of publication: China