Determination of melanotan-II in rat plasma by liquid chromatography/tandem mass spectrometry: determination of pharmacokinetic parameters in rat following intravenous administration.

Mock, S; Shen, X; Tamvakopoulos, C

Mock, S; Shen, X; Tamvakopoulos, C.

Affiliation

Mock S; Merck Research Laboratories, Rahway, NJ 07065, USA.

Rapid Commun Mass Spectrom ; 16(22): 2142-7, 2002.

Article in En | MEDLINE | ID: mdl-12415547

Subject(s)

Chromatography, Liquid/methods; Mass Spectrometry/methods; Peptides, Cyclic/blood; Peptides, Cyclic/pharmacokinetics; alpha-MSH/analogs & derivatives; alpha-MSH/blood; alpha-MSH/pharmacokinetics; Animals; Biological Availability; Infusions, Intravenous; Male; Molecular Structure; Peptides, Cyclic/administration & dosage; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; alpha-MSH/administration & dosage

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Collection: 01-internacional Database: MEDLINE Main subject: Peptides, Cyclic / Mass Spectrometry / Alpha-MSH / Chromatography, Liquid Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Rapid Commun Mass Spectrom Year: 2002 Document type: Article Affiliation country: United States Country of publication: United kingdom

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