Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats.

Falvella, F Stefania; Pascale, Rosa M; Gariboldi, Manuela; Manenti, Giacomo; De Miglio, Maria R; Simile, Maria M; Dragani, Tommaso A; Feo, Francesco

Falvella, F Stefania; Pascale, Rosa M; Gariboldi, Manuela; Manenti, Giacomo; De Miglio, Maria R; Simile, Maria M; Dragani, Tommaso A; Feo, Francesco.

Affiliation

Falvella FS; Department of Experimental Oncology, Istituto Nazionale Tumori, Via G. Venezian 1, 20133 Milan, Italy.

Carcinogenesis ; 23(11): 1933-6, 2002 Nov.

Article in En | MEDLINE | ID: mdl-12419843

Subject(s)

Liver Neoplasms, Experimental/genetics; Mice, Inbred Strains/genetics; Rats, Inbred Strains/genetics; Stearoyl-CoA Desaturase/genetics; Alleles; Animals; Chromosome Mapping; Crosses, Genetic; Enzyme Induction; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Immunity, Innate; Liver/enzymology; Liver Neoplasms, Experimental/chemically induced; Liver Neoplasms, Experimental/enzymology; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; RNA, Messenger/biosynthesis; Rats; Rats, Inbred BN; Rats, Inbred F344; Stearoyl-CoA Desaturase/biosynthesis; Urethane/toxicity

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Collection: 01-internacional Database: MEDLINE Main subject: Rats, Inbred Strains / Stearoyl-CoA Desaturase / Liver Neoplasms, Experimental / Mice, Inbred Strains Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Carcinogenesis Year: 2002 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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