Tolerance and dependence following chronic intracerebroventricular infusions of Tyr-D-Arg2-Phe-Sar4 (TAPS).

Vonhof, Stefan; Gudka, Bijal D; Sirén, Anna Leena

Vonhof, Stefan; Gudka, Bijal D; Sirén, Anna Leena.

Affiliation

Vonhof S; Department of Cardiology and Pneumology, Georg-August-University, Robert-Koch-Str. 40, 37075, Göttingen, Germany. svonhof@gwdg.de

Eur J Pharmacol ; 459(1): 41-8, 2003 Jan 10.

Article in En | MEDLINE | ID: mdl-12505532

Subject(s)

Oligopeptides/pharmacology; Pain/prevention & control; Analgesics, Opioid/pharmacology; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-/pharmacology; In Vitro Techniques; Infusion Pumps; Injections, Intraventricular; Male; Morphine/pharmacology; Naloxone/administration & dosage; Pain/physiopathology; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome/etiology; Substance Withdrawal Syndrome/physiopathology; Substance Withdrawal Syndrome/prevention & control; Substance-Related Disorders; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Pain Type of study: Etiology_studies Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2003 Document type: Article Affiliation country: Germany Country of publication: Netherlands

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