Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER.

Liao, Wei; Hui, To Y; Young, Stephen G; Davis, Roger A

Liao, Wei; Hui, To Y; Young, Stephen G; Davis, Roger A.

Affiliation

Liao W; Mammalian Cell and Molecular Biology Laboratory, San Diego State University, San Diego, CA 92182-4614, USA.

J Lipid Res ; 44(5): 978-85, 2003 May.

Article in En | MEDLINE | ID: mdl-12588952

Subject(s)

Apolipoproteins B/metabolism; Benzamides/pharmacology; Carrier Proteins/antagonists & inhibitors; Endoplasmic Reticulum/metabolism; Indenes/pharmacology; Animals; Apolipoproteins B/drug effects; Carrier Proteins/metabolism; Endoplasmic Reticulum/drug effects; Endoplasmic Reticulum Chaperone BiP; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Microsomes, Liver/drug effects; Microsomes, Liver/metabolism; Receptors, LDL/deficiency; Receptors, LDL/genetics; Triglycerides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins B / Benzamides / Carrier Proteins / Endoplasmic Reticulum / Indenes Limits: Animals Language: En Journal: J Lipid Res Year: 2003 Document type: Article Affiliation country: United States Country of publication: United States

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