Oral-antigen delivery via a water-in-oil emulsion system modulates the balance of the Th1/Th2 type response in oral tolerance.

Masuda, Kazuyoshi; Horie, Kazutoshi; Suzuki, Ryuji; Yoshikawa, Takayoshi; Hirano, Koichiro

Masuda, Kazuyoshi; Horie, Kazutoshi; Suzuki, Ryuji; Yoshikawa, Takayoshi; Hirano, Koichiro.

Affiliation

Masuda K; Shionogi Research Laboratories, Shionogi & Co., Ltd., 5-124, Sagisu, Fukushima-ku, Osaka 553-0002, Japan. kazuyoshi.masuda@shionogi.co.jp

Pharm Res ; 20(1): 130-4, 2003 Jan.

Article in En | MEDLINE | ID: mdl-12608547

Subject(s)

Antigens/administration & dosage; Drug Delivery Systems/methods; Emulsions/administration & dosage; Oils; Th1 Cells/drug effects; Th1 Cells/metabolism; Th2 Cells/drug effects; Th2 Cells/metabolism; Water; Administration, Oral; Animals; Drug Tolerance/physiology; Immunoglobulin G/biosynthesis; Immunoglobulin G/blood; Interferon-gamma/metabolism; Interleukin-4/metabolism; Lymph Nodes/cytology; Lymph Nodes/drug effects; Lymph Nodes/metabolism; Male; Mice; Mice, Inbred BALB C; Oils/administration & dosage; Ovalbumin/administration & dosage; Water/administration & dosage

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Collection: 01-internacional Database: MEDLINE Main subject: Oils / Water / Drug Delivery Systems / Th2 Cells / Th1 Cells / Emulsions / Antigens Type of study: Prognostic_studies Limits: Animals Language: En Journal: Pharm Res Year: 2003 Document type: Article Affiliation country: Japan

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