Optimisation of cell-based assays for medium throughput screening of oxidative stress.

Lautraite, S; Bigot-Lasserre, D; Bars, R; Carmichael, N

Lautraite, S; Bigot-Lasserre, D; Bars, R; Carmichael, N.

Affiliation

Lautraite S; Bayer CropScience, 355 rue Dostoïevski BP 153 06903 Sophia-Antipolis cedex, France. sophie.lautraite@bayercropscience.com

Toxicol In Vitro ; 17(2): 207-20, 2003 Apr.

Article in En | MEDLINE | ID: mdl-12650675

Subject(s)

Liver/drug effects; Oxidative Stress/drug effects; Animals; Cell Membrane/drug effects; Cell Survival/drug effects; Cells, Cultured; Fluoresceins; Glutathione/metabolism; Glutathione Peroxidase/metabolism; Hepatocytes/drug effects; Liver/enzymology; Liver/metabolism; Liver/pathology; Male; Membrane Potentials/drug effects; Mitochondria/drug effects; Mitochondria/metabolism; Mitochondria/pathology; Rats; Rats, Wistar; Rhodamine 123; tert-Butylhydroperoxide/toxicity

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Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Liver Type of study: Diagnostic_studies / Screening_studies Limits: Animals Language: En Journal: Toxicol In Vitro Journal subject: TOXICOLOGIA Year: 2003 Document type: Article Affiliation country: France

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