Accurate mass measurement by electrospray ionization quadrupole mass spectrometry: detection of variants differing by <6 Da from normal in human hemoglobin heterozygotes.

Rai, Dilip K; Griffiths, William J; Landin, Britta; Wild, Barbara J; Alvelius, Gunvor; Green, Brian N

Rai, Dilip K; Griffiths, William J; Landin, Britta; Wild, Barbara J; Alvelius, Gunvor; Green, Brian N.

Affiliation

Rai DK; Division of Clinical Chemistry, Department of Medical Laboratory Sciences and Technology, Huddinge University Hospital C1 74, Karolinska Institutet, SE-141 86 Stockholm, Sweden. dilip.rai@labmed.ki.se

Anal Chem ; 75(9): 1978-82, 2003 May 01.

Article in En | MEDLINE | ID: mdl-12720330

Subject(s)

Hemoglobins, Abnormal/chemistry; Hemoglobins, Abnormal/genetics; Calibration; Electrophoresis; Heterozygote; Humans; Mutation/genetics; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

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Collection: 01-internacional Database: MEDLINE Main subject: Hemoglobins, Abnormal Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Anal Chem Year: 2003 Document type: Article Affiliation country: Sweden Country of publication: United States

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