Involvement of the electrophile responsive element and p53 in the activation of hepatic stellate cells as a response to electrophile menadione.

Vasiliou, Vasilis; Qamar, Lubna; Pappa, Aglaia; Sophos, Nickolas A; Petersen, Dennis R

Vasiliou, Vasilis; Qamar, Lubna; Pappa, Aglaia; Sophos, Nickolas A; Petersen, Dennis R.

Affiliation

Vasiliou V; Molecular Toxicology and Environmental Health Sciences Program, Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, P.O. Box C238, Denver, CO 80262, USA. vasilis.vasiliou@uchsc.edu

Arch Biochem Biophys ; 413(2): 164-71, 2003 May 15.

Article in En | MEDLINE | ID: mdl-12729613

Subject(s)

Liver/drug effects; Liver/metabolism; Tumor Suppressor Protein p53/metabolism; Vitamin K 3/pharmacology; Animals; Anions; Blotting, Western; Cell Nucleus/metabolism; Cell Survival; Cytosol/metabolism; DNA-Binding Proteins/metabolism; Dose-Response Relationship, Drug; Fibrosis/metabolism; Luciferases/metabolism; NAD(P)H Dehydrogenase (Quinone)/metabolism; NF-E2-Related Factor 1; NF-E2-Related Factor 2; Nuclear Respiratory Factor 1; Nuclear Respiratory Factors; Plasmids/metabolism; Protein Binding; Quinone Reductases/metabolism; Rats; Signal Transduction; Subcellular Fractions; Superoxides/metabolism; Trans-Activators/metabolism; Transfection; Up-Regulation

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Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Vitamin K 3 / Liver Type of study: Prognostic_studies Limits: Animals Language: En Journal: Arch Biochem Biophys Year: 2003 Document type: Article Affiliation country: United States Country of publication: United States

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